Experimental study on the law of rupture of pig eardrum based on free-field explosion

XIANG Shuyi; XUE Songbo; DU Zhibo; ZHAO Yang; WANG Xinghao; TIAN Xu; GAO Zhiqiang; FENG Guodong; FEI Zhou; ZHUANG Zhuo; LIU Zhanli

doi:10.11883/bzycj-2024-0255

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XIANG Shuyi, XUE Songbo, DU Zhibo, ZHAO Yang, WANG Xinghao, TIAN Xu, GAO Zhiqiang, FENG Guodong, FEI Zhou, ZHUANG Zhuo, LIU Zhanli. Experimental study on the law of rupture of pig eardrum based on free-field explosion[J]. Explosion And Shock Waves. doi: 10.11883/bzycj-2024-0255

Citation:

XIANG Shuyi, XUE Songbo, DU Zhibo, ZHAO Yang, WANG Xinghao, TIAN Xu, GAO Zhiqiang, FENG Guodong, FEI Zhou, ZHUANG Zhuo, LIU Zhanli. Experimental study on the law of rupture of pig eardrum based on free-field explosion[J]. Explosion And Shock Waves. doi: 10.11883/bzycj-2024-0255

Citation:

XIANG Shuyi, XUE Songbo, DU Zhibo, ZHAO Yang, WANG Xinghao, TIAN Xu, GAO Zhiqiang, FENG Guodong, FEI Zhou, ZHUANG Zhuo, LIU Zhanli. Experimental study on the law of rupture of pig eardrum based on free-field explosion[J]. Explosion And Shock Waves. doi: 10.11883/bzycj-2024-0255

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Experimental study on the law of rupture of pig eardrum based on free-field explosion

doi: 10.11883/bzycj-2024-0255

1.
School of Aerospace Engineering, Tsinghua University, Beijing 100084, China
2.
Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
3.
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
4.
Xijing Hospital, Air Force Military Medical University, Xi’an 710032, Shaanxi, China

Received Date: 2024-07-24
Rev Recd Date: 2024-09-23

Available Online: 2024-10-08

Abstract

Abstract

Mechanical damage to components of the auditory system is the main cause of hearing loss after exposure to blast overpressure waves. There still exist some controversies in high level impulse sound Damage Risk Criteria (DRC). For example, whether average energy or peak overpressure should be used as a main criterion, whether positive duration is important or not, etc. Based on the free-field air explosion, we designed and established a platform for studying blast injuries in large animals. We studied the effect of different explosion parameters on the rupture of the tympanic membrane (TM) and established a relationship between the probability of TM rupture and the dose of the blast wave in terms of peak overpressure and positive duration. The free-field overpressure time history was measured by a pen-shaped pressure sensor. The overpressure time-history curves were fitted by the modified Friedlander equation, thus the peak pressure and positive duration of the blast wave were determined. The impulse pressure energy spectra analysis is performed on the recorded waveforms to determine the signal energy distribution over the frequencies under different explosion parameters. The degree of TM rupture of miniature pigs was recorded after dissection. A two-variable logistic regression was performed on the resulting experimental TM rupture ratio for damage risk curves in terms of peak overpressure and positive duration. The study found that when peak overpressure was lower than 170kPa, there was no obvious damage to the TM; when peak overpressure was greater than 237 kPa, some of the TMs ruptured or were congested with varying severity. As the distance from the explosion center became smaller, the peak pressure became larger, while the severity of TM damage did not increase monotonically. In the 8.0-kg-TNT equivalent explosion, the severity of TM rupture showed a tendency to increase and then decrease as the distance became smaller. Through the analysis of the blast wave characteristics, we found that the smaller the distance away from the center, the shorter the positive duration and the increase in the high-frequency component of the blast wave. The probability of TM rupture of miniature pigs may decrease, but significant hearing loss and inner ear damage still occur at this time. As a viscoelastic membrane structure that transmits sound through vibration, the dynamic response of the eardrum may be closely related to the frequency spectrum of loads. In addition to the peak pressure, the blast wave waveform may have a significant impact on the degree of TM rupture.
- free-field explosion,
- blast wave,
- tympanic membrane rupture,
- hearing loss,
- damage risk

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References(37)

References

[1]	GAN R Z, NAKMALI D, JI X D, et al. Mechanical damage of tympanic membrane in relation to impulse pressure waveform–A study in chinchillas [J]. Hearing Research, 2016, 340: 25–34. DOI: 10.1016/j.heares.2016.01.004.
[2]	GAN R Z, LECKNESS K, NAKMALI D, et al. Biomechanical measurement and modeling of human eardrum injury in relation to blast wave direction [J]. Military Medicine, 2018, 183(S1): 245–251. DOI: 10.1093/milmed/usx149.
[3]	GAN R Z, LECKNESS K, SMITH K, et al. Characterization of protection mechanisms to blast overpressure for personal hearing protection devices–Biomechanical measurement and computational modeling [J]. Military Medicine, 2019, 184(S1): 251–260. DOI: 10.1093/milmed/usy299.
[4]	LECKNESS K, NAKMALI D, GAN R Z. Computational modeling of blast wave transmission through human ear [J]. Military Medicine, 2018, 183(S1): 262–268. DOI: 10.1093/milmed/usx226.
[5]	BROWN M A, JI X D, GAN R Z. 3D Finite element modeling of blast wave transmission from the external ear to cochlea [J]. Annals of Biomedical Engineering, 2021, 49(2): 757–768. DOI: 10.1007/s10439-020-02612-y.
[6]	BROWN M A, BRADSHAW J J, GAN R Z. Three-dimensional finite element modeling of blast wave transmission from the external ear to a spiral cochlea [J]. Journal of Biomechanical Engineering, 2022, 144(1): 014503. DOI: 10.1115/1.4051925.
[7]	BRADSHAW J J, BROWN M A, JIANG S Y, et al. 3D finite element model of human ear with 3-Chamber spiral cochlea for blast wave transmission from the ear canal to cochlea [J]. Annals of Biomedical Engineering, 2023, 51(5): 1106–1118. DOI: 10.1007/s10439-023-03200-6.
[8]	JIANG S Y, SMITH K, GAN R Z. Dual-laser measurement and finite element modeling of human tympanic membrane motion under blast exposure [J]. Hearing Research, 2019, 378: 43–52. DOI: 10.1016/j.heares.2018.12.003.
[9]	JIANG S Y, DAI C K, GAN R Z. Dual-laser measurement of human stapes footplate motion under blast exposure [J]. Hearing Research, 2021, 403: 108177. DOI: 10.1016/j.heares.2021.108177.
[10]	BIEN A G, JIANG S Y, GAN R Z. Real-time measurement of stapes motion and intracochlear pressure during blast exposure [J]. Hearing Research, 2023, 429: 108702. DOI: 10.1016/j.heares.2023.108702.
[11]	GAN R Z, JIANG S Y. Surface motion changes of tympanic membrane damaged by blast waves [J]. Journal of Biomechanical Engineering, 2019, 141(9): 091009. DOI: 10.1115/1.4044052.
[12]	LUO H Y, DAI C K, GAN R Z, et al. Measurement of young’s modulus of human tympanic membrane at high strain rates [J]. Journal of Biomechanical Engineering, 2009, 131(6): 064501. DOI: 10.1115/1.3118770.
[13]	LUO H Y, JIANG S Y, NAKMALI D U, et al. Mechanical properties of a human eardrum at high strain rates after exposure to blast waves [J]. Journal of Dynamic Behavior of Materials, 2016, 2(1): 59–73. DOI: 10.1007/s40870-015-0041-3.
[14]	ENGLES W G, WANG X L, GAN R Z. Dynamic properties of human tympanic membrane after exposure to blast waves [J]. Annals of Biomedical Engineering, 2017, 45(10): 2383–2394. DOI: 10.1007/s10439-017-1870-0.
[15]	LIANG J F, LUO H Y, YOKELL Z, et al. Characterization of the nonlinear elastic behavior of chinchilla tympanic membrane using micro-fringe projection [J]. Hearing Research, 2016, 339: 1–11. DOI: 10.1016/j.heares.2016.05.012.
[16]	LIANG J F, YOKELL Z A, NAKMAILI D U, et al. The effect of blast overpressure on the mechanical properties of a chinchilla tympanic membrane [J]. Hearing Research, 2017, 354: 48–55. DOI: 10.1016/j.heares.2017.08.003.
[17]	LIANG J F, SMITH K D, GAN R Z, et al. The effect of blast overpressure on the mechanical properties of the human tympanic membrane [J]. Journal of the Mechanical Behavior of Biomedical Materials, 2019, 100: 103368. DOI: 10.1016/j.jmbbm.2019.07.026.
[18]	CHEN T, SMITH K, JIANG S Y, et al. Progressive hearing damage after exposure to repeated low-intensity blasts in chinchillas [J]. Hearing Research, 2019, 378: 33–42. DOI: 10.1016/j.heares.2019.01.010.
[19]	SMITH K D, CHEN T, GAN R Z. Hearing damage induced by blast overpressure at mild TBI level in a chinchilla model [J]. Military Medicine, 2020, 185(S1): 248–255. DOI: 10.1093/milmed/usz309.
[20]	JIANG S Y, GANNON A N, SMITH K D, et al. Prevention of blast-induced auditory injury using 3D printed helmet and hearing protection device–A preliminary study on biomechanical modeling and animal [J]. Military Medicine, 2021, 186(S1): 537–545. DOI: 10.1093/milmed/usaa317.
[21]	SHAO N N, JIANG S Y, YOUNGER D, et al. Central and peripheral auditory abnormalities in chinchilla animal model of blast-injury [J]. Hearing Research, 2021, 407: 108273. DOI: 10.1016/j.heares.2021.108273.
[22]	DEWEY J M. The shape of the blast wave: studies of the Friedlander equation [C]//Proceedings of the 21st International Symposium on Military Aspects of Blast and Shock. 2010: 1–9.
[23]	FRIEDLANDER F G. The diffraction of sound pulses I. Diffraction by a semi-infinite plane [J]. Proceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences, 1946, 186(1006): 322–344. DOI: 10.1098/rspa.1946.0046.
[24]	IYOHO A E, HO K, CHAN P. The development of a tympanic membrane model and probabilistic dose-response risk assessment of rupture because of blast [J]. Military Medicine, 2020, 185(S1): 234–242. DOI: 10.1093/milmed/usz215.
[25]	YOUNG R W. On the energy transported with a sound pulse [J]. The Journal of the Acoustical Society of America, 1970, 47(2A): 441–442. DOI: 10.1121/1.1911547.
[26]	RAFAELS K, BASS C, SALZAR R S, et al. Survival risk assessment for primary blast exposures to the head [J]. Journal of Neurotrauma, 2011, 28: 2319–2328. DOI: 10.1089/neu.2009.1207.
[27]	ZHU F, CHOU C C, YANG K H, et al. Some considerations on the threshold and inter-species scaling law for primary blast-induced traumatic brain injury: a semi-analytical approach [J]. Journal of Mechanics in Medicine and Biology, 2013, 13(4): 1350065. DOI: 10.1142/S0219519413500656.
[28]	KOIKE T, WADA H, ITO F, et al. High-speed video observation of tympanic membrane rupture in guinea pigs [J]. JSME International Journal Series C Mechanical Systems, Machine Elements and Manufacturing, 2003, 46(4): 1434–1440. DOI: 10.1299/jsmec.46.1434.
[29]	JENSEN J H, BONDING P. Experimental pressure induced rupture of the tympanic membrane in man [J]. Acta Oto-Laryngologica, 1993, 113(1): 62–67. DOI: 10.3109/00016489309135768.
[30]	张洁元. 爆炸冲击波致豚鼠听觉和前庭功能损害评估技术与标准研究 [D]. 重庆: 陆军军医大学, 2022. DOI: 10.27001/d.cnki.gtjyu.2022.000239. ZHANG J Y. Evaluation techniques and criteria for auditory and vestibular function impairment caused by blast shock waves in guinea pigs [D]. Chongqing: Army Medical University, 2022. DOI: 10.27001/d.cnki.gtjyu.2022.000239.
[31]	AMREIN B E, LETOWSKI T R. High level impulse sounds and human hearing: standards, physiology, quantification: ARL-TR-6017 [R]. Affiliation: U. S. Army Research Laboratory, 2012.
[32]	CULLIS I G. Blast waves and how they interact with structures [J]. BMJ Military Health, 2001, 147(1): 16–26. DOI: 10.1136/jramc-147-01-02.
[33]	PADURARIU S, DE GREEF D, JACOBSEN H, et al. Pressure buffering by the tympanic membrane. In vivo measurements of middle ear pressure fluctuations during elevator motion [J]. Hearing Research, 2016, 340: 113–120. DOI: 10.1016/j.heares.2015.12.004.
[34]	XIE P P, PENG Y, HU J J, et al. Assessment of hearing loss induced by tympanic membrane perforations under blast environment [J]. European Archives of Oto-Rhino-Laryngology, 2020, 277(2): 453–461. DOI: 10.1007/s00405-019-05710-3.
[35]	LITTLEFIELD P D, BRUNGART D S. Long-term sensorineural hearing loss in patients with blast-induced tympanic membrane perforations [J]. Ear and Hearing, 2020, 41(1): 165–172. DOI: 10.1097/AUD.0000000000000751.
[36]	FAY J, PURIA S, DECRAEMER W F, et al. Three approaches for estimating the elastic modulus of the tympanic membrane [J]. Journal of Biomechanics, 2005, 38(9): 1807–1815. DOI: 10.1016/j.jbiomech.2004.08.022.
[37]	PRICE G R, KIM H N, LIM D J, et al. Hazard from weapons impulses: histological and electrophysiological evidence [J]. The Journal of the Acoustical Society of America, 1989, 85(3): 1245–1254. DOI: 10.1121/1.397455.