Abstract: The quasi-static and dynamic compression behavior of beryllium was investigated using MTS and SHPB at different temperatures. Investigated results show that beryllium exhibits excellent plasticity under compression. Sensitive to the changes in temperature and strain rate, the yield point and flow stress of beryllium have an marked tendency to increase with the increase of the strain rate, and to decrease gradually with the rise of temperatures. At the same time, the work hardening behavior of beryllium exhibits a piecewise hardening feature as the strain increases at room temperature, and tends to become smooth as the temperature rises. Finally, a modified Johnson-Cook constitutive model was developed to predict the deformation behavior of beryllium over a wide range of temperatures and strain rates. The calculation results of the model are in good agreement with those achieved from the experiment.