Abstract: In order to study the damage mechanism of Zr-based amorphous alloy fragments penetrating CFRP and the destructive ability of the target material, a ballistic gun test was carried out to examine the ballistic performance of spherical Zr-based amorphous alloy. The area of the post-effect target of LY12 was analyzed using image recognition technology, with the aim of determining the extent of damage caused by the penetration of Zr-based amorphous alloy fragments through the laminated target and interstitial target, which was composed of 6mm-thick CFRP and 2mm-thick LY12. The results demonstrate that the damage area of the CFRP target is proportional to the fragmentation speed. There is no discernible reaction on the remaining portion of the target, with damage observed on the facing side, characterized by fiber shear and compression deformation, and on the backside, exhibiting tensile tearing and inter laminar failure. As the speed increases, the proportion of shear damage to the CFRP gradually increases. When a fragment impacts a target plate of the same setup, the damaged area of the LY12 target increases with the speed. When the speed is below 954.7 m·s-1, the damaged area of the interstitial target post-effect LY12 target is smaller than that of the laminated target post-effect LY12 target. With the increase of speed, the damaged area of the interstitial target post-effect LY12 target improves rapidly, while the damaged area of the laminated target post-effect LY12 target increases rapidly. The growth of the damaged area of the interstitial target post-effect LY12 target tends to slow down, and the former is much larger than the latter. Therefore, it is more favorable to set up interstitial targets for post-effect damage in high-speed impacts.