The dynamic responses of discrete multilayered wound ribbon vessels(DMWRV) subjected to internal explosion loading were numerically simulated by using LS-DYNA3D. Several kinds of winding angles were considered. The simulated results were compared with the experimental results, theoretical analysis and numerical results of a monobloc thick-walled high-pressure vessel. Compared results indicate the following: (1) the stress distribution in the ribbon layers of DMWRV is homogeneous; (2) the bigger the winding angle is, the bigger the final displacement of the outermost layer is subjected to the same TNT; (3) the DMWRV has excellent property of leak before burst at worst, which is impossible for the monobloc thick-walled high pressure vessel. Simulated results are helpful to establish the engineering design criteria of the explosion containment vessels.